Multiple sclerosis (abbreviated MS , also known as disseminated sclerosis ) is a chronic , inflammatory disease that affects the central nervous system (CNS) . Although many patients lead full and rewarding lives, MS can cause impaired mobility and disability in more severe cases. The name multiple sclerosis refers to the multiple scars (or scleroses) on the myelin sheaths. Doctors and researchers think the illness is probably an autoimmune disease, which means that your immune system attacks part of your body as if it's a foreign substance. Your immune system attacks your CNS, specifically, a fatty tissue of the CNS called myelin Sometimes, in most severe cases the nerve fibers themselves will be affected, and not only the myelin.
Multiple sclerosis affects more than 1 million people around the world - including twice as many women as men. which means that your immune system attacks part of your body as if it's a foreign substance.. The result may be multiple areas of scarring (sclerosis)
Cause of Multiple Sclerosis
Some Cause of Multiple Sclerosis:
Symptoms of Multiple Sclerosis
Some sign and Symptoms related to Multiple Sclerosisare as follows:
Treatment of Multiple Sclerosis
At least partial recovery from acute exacerbations can reasonably be expected, but further relapses may occur without warning, and there is no means of preventing progression of the disorder. Some disability is likely to result eventually, but about half of all patients are without significant disability even 10 years after onset of symptoms. In some people, MS is a mild illness, but, for others, it results in permanent disability. Treatments can modify the course of the disease and relieve symptoms.
Recovery from acute relapses may be hastened by treatment with corticosteroids, but the extent of recovery is unchanged. A high dose (eg, prednisone, 60 or 80 mg) is given daily for 1 week, after which medication is tapered over the following 2 or 3 weeks. Such a regimen is often preceded by methylprednisolone, 1 g intravenously for 3 days. Long-term treatment with steroids provides no benefit and does not prevent further relapses. Other drugs that may reduce fatigue in some, but not all, patients include amantadine (Symmetrel), pemoline (Cylert), and the still-experimental drug aminopyridine. Although improvement of optic symptoms usually occurs even without treatment, a short course of treatment with intravenous methylprednisolone (Solu-Medrol) followed by treatment with oral steroids is sometimes used.
In patients with relapsing-remitting or secondary progressive disease, treatment with -interferon or with daily subcutaneous administration of glatiramer acetate reduces the frequency of exacerbations. Several recent studies have suggested that immunosuppressive therapy with cyclophosphamide, azathioprine, methotrexate, cladribine, or mitoxantrone may help to arrest the course of secondary progressive multiple sclerosis. The evidence of benefit is incomplete, however. There is little evidence that plasmapheresis enhances any beneficial effects of immunosuppression in multiple sclerosis. Intravenous immunoglobulins may reduce the clinical attack rate in relapsing-remitting disease, but the available studies are inadequate to permit treatment recommendations. Some useful treatment methods of Multiple Sclerosis
Disclaimer : All information on www.healthatoz.info is for educational purposes only. It is not a substitute for professional medical advice. For specific medical advice, diagnoses, and treatment, please consult your doctor.