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Generic Name

  • Quinapril

Brand names

  • Accupril

General Information

Accupril is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Accupril comes as a tablet to take by mouth. It is usually taken once or twice a day. To help you remember to take quinapril, take it around the same time every day. It is used in combination with other medications to treat heart failure. Quinapril is in a class of medications called angiotensin-converting enzyme inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently. Accupril controls high blood pressure and heart failure but does not cure them. Continue to take quinapril even if you feel well. Do not stop taking quinapril without talking to your doctor. Alcohol may increase the effect of Accupril, and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor. Accupril may also be used for purposes other than those listed in this medication guide. Accupril also enhances blood flow throughout your blood vessels. Along with other drugs, Accupril is also prescribed in the treatment of congestive heart failure.

Accupril Dosage

  • The recommended initial dosage of accupril in patients not on diuretics is 10 mg once daily.
  • In patients who are also being treated with a diuretic, the initial dosage of accupril is 5 mg in order to determine if excess hypotension will occur.

Side Effects of Accupril

The following side effects of Accupril may includes:

  • Excessive tiredness.
  • Upset stomach.
  • Difficulty breathing or swallowing.
  • Dizziness.
  • Yellowing of the skin or eyes.
  • Lightheadedness.
  • Headache.

Warnings and precautions before taking Accupril

  • Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.
  • Tell your doctor if you plan to become pregnant or are breast-feeding.
  • If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking quinapril.
  • If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.
  • Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
  • If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.


  • Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
  • A severe drop in blood pressure is the primary sign of an Accupril overdose.
  • US residents can call the US national poison hotline at 1-800-222-1222.
  • Canadian residents should call their local poison control center directly.



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