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Ganirelix Acetate

Generic Name

  • Ganirelix Acetate.

Brand Names

  • Antagon.

General Information

Ganirelix Acetate (Antagon) is a man-made protein that inhibits the actions of the naturally-occurring hormone gonadotropin-releasing hormone. Ganirelix is used along with other medications to regulate hormone response in the treatment of infertility in women. Ganirelix is used as a fertility medicine to prevent premature luteinizing hormone surges in women undergoing the fertility procedure of controlled ovarian hyperstimulation. Luteinizing hormone is involved in ovulation, which is the development of eggs in the ovaries. Ganirelix may help reduce the need for follicle-stimulating hormone, which is also involved in ovulation. Ganirelix acetate works immediately by suppressing luteinizing hormone and FSH secretion. This allows for eggs to reach the level of development needed for fertilization. Ganirelix should be prescribed by a doctor experienced in infertility treatment. Before starting treatment with ganirelix, it should be determined that you are not already pregnant. Ganirelix may be harmful to an unborn baby.

Ganirelix Acetate Dosage

  • The dose of ganirelix-acetate will be different for different patients.

For treatment of female infertility:

  • For adults - After receiving FSH treatment on day 2 or 3 of your menstrual cycle, 250 micrograms of ganirelix is injected under the skin once a day during the early to midfollicular phase.

Side Effects of Ganirelix Acetate

Some common side effects reported with this medicine include:

  • Abdominal pain.
  • Headache.
  • Weight gain.
  • Nausea and vomiting.
  • Diarrhea.
  • Shortness of breath.

Warnings and precautions before taking Ganirelix Acetate

  • Tell your doctor if you have ever had any unusual or allergic reaction to ganirelix acetate or other related medicines.
  • Ganirelix acetate is not recommended during pregnancy. It has been shown to cause problems in animals. Be sure you have discussed this with your doctor.
  • Do not receive the injection of human chorionic gonadotropin.
  • The presence of other medical problems may affect the use of ganirelix acetate. Make sure you tell your doctor if you have any other medical problems.
  • Do not take ganirelix without first talking to your doctor if you are breast-feeding a baby.


  • An overdose of ganirelix is unlikely to threaten life. Notify your doctor immediately or call an emergency room or poison control left for advice if an overdose is suspected.
  • Symptoms of a ganirelix overdose are not known.



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