Hofseth BioCare gut health product backed by study

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Oct 19, 2022

Published in the peer-reviewed journal Biomolecules by MDPI, the study was conducted through a collaboration between Hofseth BioCare (HBC) and Stanford University School of Medicine

Norwegian biotech company Hofseth BioCare has revealed a Stanford University study that illustrates the effectiveness of its ingredient ProGo for gut health.

The study, published in the peer-reviewed journal Biomolecules by MDPI, was conducted through a collaboration between Hofseth BioCare (HBC) and Stanford University School of Medicine.

It aimed to further investigate the gastrointestinal (GI) protective properties of bioactive peptides contained in salmon-derived ProGo. The preclinical study revealed that Soluble Protein Hydrolyzate (SPH) powder, produced by HBC’s unique enzymatic protein hydrolysis process, helps restore a healthy balance within the gut immune system and significantly improves overall health. bowel disease in inflammatory bowel disease (IBD).

Bioactive peptides from SPH significantly reduced colonic tissue damage in the animal model of acute colitis by alleviating inflammatory cellular infiltrates and oxidative stress, an underlying driver of many digestive diseases. This indicates that ProGo has potential immunomodulatory action through upregulation of protective and antioxidant genetic pathways, including HMOX1.

The peptides that make up ProGo have been proven to provide not only nutritional benefits, such as collagen for skin health, but also a myriad of important health benefits.

Previous research undertaken by HBC and Stanford has also demonstrated that gene systems that protect the gastrointestinal tract against oxidative stress and inflammation are up-regulated in human GI cells exposed to HPS. This latest discovery reinforces ProGo’s position as a fresh and effective innovation and presents a prime opportunity for nutraceutical manufacturers looking to disrupt the gut health and immunity markets.

“The peptides that make up ProGo have been proven to provide not only nutritional benefits, such as collagen for skin health, but also a myriad of important health benefits, including antioxidant effects to support health and intestinal immunity and to maintain overall health,” said Dr. Crawford. Currie, head of medical R&D at Hofseth BioCare.

Currie continued, “This latest study from Stanford University reinforces ProGo’s reputation as a patented product with unique properties, claims and health benefits in the marketplace. Further clinical studies are underway to explore the effectiveness of ProGo as a functional and targeted tool in the management of IBD and we look forward to discovering the full potential of this truly transformative innovation.

The study adds to the growing bank of evidence demonstrating that ProGo is a pure, proven product. The ingredient was recently recognized as a “New Food Ingredient” (NDI) and was granted seven new structure and function claims by the United States Food and Drug Administration (FDA).

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These natural collagen peptides can now be claimed to help “reduce wrinkles and promote smooth skin”, “help dry skin”, and “support skin health and appearance”. Additionally, evidence of peptide bioactivity can now claim to “act as an antioxidant”, “reduce oxidative stress caused by free radicals”, as well as support energy and maintain overall health and well-being.

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