Pernicious Anemia Alternative names is Macrocytic achylic anemia and Congenital pernicious anemia. Pernicious anemia is a chronic illness caused by impaired absorption of vitamin B-12. Vitamin B-12 is necessary for the formation of red blood cells. Pernicious anemia occurs as a relatively common adult form of anemia that is associated with gastric atrophy and a loss of IF production and as a rare congenital autosomal recessive form in which IF production is lacking without gastric atrophy. Anemia is a condition where red blood cells are not providing adequate oxygen to body tissues.
There are many types and causes of anemia. Intrinsic factor is a protein that helps the body absorb vitamin B-12. When stomach secretions do not have enough intrinsic factor, vitamin B-12 is not absorbed well. This results in pernicious anemia and other problems related to low levels of vitamin B-12. Pernicious anemia is therefore one of the types of megaloblastic anemia. The most common symptoms for megaloblastic (pernicious) anemia. However, each individual may experience symptoms differently.
Pernicious anemia are feeling tired and weak and having a bright red, smooth tongue. Common symptoms of nerve damage caused by this disease are tingling and numbness in the hands and feet.
Anemia is a condition where red blood cells are not providing adequate oxygen to body tissues. Absence of intrinsic factor itself is the most common cause of vitamin B-12 deficiency. Intrinsic factor is produced by cells in the stomach. In adults, the inability to make intrinsic factor can be the result of chronic gastritis or the result of surgery to remove the stomach.
The onset of the disease is slow and may take decades. While the term pernicious anemia is reserved for patients with vitamin B-12 deficiency due to a lack of production of IF in the stomach, vitamin B-12 absorption is complex and other causes of vitamin B-12 deficiency exist and are described briefly in this article. There are many types and causes of anemia. (See the general article - anemia ).
Causes of Pernicious Anemia
Common causes of Pernicious Anemia
Symptoms of Pernicious Anemia
Common Symptoms of Pernicious Anemia
Treatment of Pernicious Anemia
Common Treatment of Pernicious Anemia
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