Thrombocytopenia is the presence of relatively few platelets in blood. The most common causes of decreased platelet production are marrow aplasia (when the marrow is not developing naturally), fibrosis (an abnormal formation) or infiltration with malignant cells.
People with low levels of platelets bleed more easily and are prone to bruising. Platelets (thrombocytes) are colorless blood cells that play an important role in blood clotting. The number of platelets in a blood sample also decreases rather quickly with time and a low platelet count may be caused by a delay between sampling and analysis. thrombocytopenia may result from the use of certain drugs, such as quinine, quinidine, rifampin, heparin, nonsteroidal anti-inflammatory agents, histamine blockers, most chemotherapeutic agents, allopurinol and alcohol.
Person with thrombocytopenia may also complain of malaise, fatigue and general weakness (with or without accompanying blood loss). In acquired thrombocytopenia, the patient's history may include the use of one or several offending drugs.
Thrombocytopenia often occurs as a result of a separate disease or disorder. For example, a bone marrow disorder such as leukemia can interfere with platelet production and reduce the number of platelets in your blood. Platelets and red and white blood cells are made in the bone marrow, a spongy, fatty tissue found on the inside of larger bones. Certain types of chemotherapy drugs can damage the bone marrow so that it does not make enough platelets. Sometimes, thrombocytopenia occurs because of an immune system malfunction that develops for unknown reasons.
Causes of Thrombocytopenia
Common causes of Thrombocytopenia
Symptoms of Thrombocytopenia
Common Symptoms of Thrombocytopenia
Treatment of Thrombocytopenia
Common Treatment of Thrombocytopenia
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