Ichthyosis - Symptoms and Treatment
Ichthyosis is a family of dermatological conditions seen in humans and domestic animals. Its literal translation is " fish skin", since people or animals with ichthyosis have scaly skin which can vaguely resemble the scales of a fish. Ichthyosis vulgaris, accounts for 95% of all ichthyosis cases. Inheritance is autosomal dominant i.e. it is passed from a parent to about half their children. Signs and symptoms of ichthyosis vulgaris usually become apparent within the first year of life. The other main forms of inherited ichthyosis include lamellar ichthyosis, epidermolytic hyperkeratosis, and X-linked ichthyosis. Acquired ichthyosis is not inherited and occurs for the first time in adulthood. It is usually associated with some general systemic disease, such as underactive thyroid states , sarcoidosis , lymphoma, generalised cancer or HIV infection . It may be provoked by certain medications (such as kava, nicotinic acid and hydroxyurea ).
Ichthyosis is the term for severe, persistent problems due to an abnormality of the outermost part of the skin, the epidermis. Ichthyosis causes the skin to build up and scale, causing it to be extremely dry, amongst other problems. Ichthyosis scaling can be very painful, can restrict the body's range of movement, cause deep cracks or fissures at the joints, and affect hearing. Ichthyosis almost start in childhood or infancy, or may develop later. Normally body continuously renews its skin surface making new skin cells and shed the older ones from the surface. But ichthyosis disturb this balance either bcurs ecause too many new skin cells are produced or because the skin cells do not separate well from the skin surface when it is their time to drop off. This results in thick flakes that adhere to the body and can resemble fish scales. It ocas a result of a number of different genetic disorders. There are different forms of Ichthyosis. The X-linked type is caused by steroid sulfatase (STS) deficiency. 90% of patients with X-linked Ichthyosis have either complete or partial deletion of the STS gene located on the X chromosome. X-linked Ichthyosis rarely occurs among females and their symptoms a generally less pronounced. Couples with a familial history of Ichthyosis may take advantage of a new technology called Pre-Implantation Genetic Diagnosis (PGD).
Causes of Ichthyosis
Common Causes of Ichthyosis :
Symptoms of Ichthyosis
The common causes and risk factor's of Ichthyosis include the following:
Treatment of Ichthyosis
Disclaimer : All information on www.healthatoz.info is for educational purposes only. It is not a substitute for professional medical advice. For specific medical advice, diagnoses, and treatment, please consult your doctor.