Mucocutaneous Candidiasis - Symptoms and Treatment
Mucocutaneous Candidiasis (MC) refers to a condition caused by a fungus from the candida family (lives on the surface of skin) that develops a diffuse and persistent type of infection of the mouth, nails, skin, and at times other organs. It may be secondary to one of the immunodeficiency syndromes, inherited as an autosomal recessive trait. Candida is a fungus of the yeast category. Chronic mucocutaneous candidiasis is a form of candidiasis that usually develops during the first year of life but occasionally occurs as late as the 20s. Affecting males and females, it's characterized by repeated infection with Candida albicans that may result from an inherited defect in cell-mediated (T-cell) immunity. In some patients, an autoimmune response affecting the endocrine system may induce various endocrinopathies. Despite chronic candidiasis, these patients seldom die of systemic infection. Instead, they usually die of hepatic or endocrine failure. The prognosis for chronic mucocutaneous candidiasis depends on the severity of the associated endocrinopathy. Patients with associated endocrinopathy seldom live beyond their 30s. Usually, the infections can be treated with an antifungal drug nystatin or clotrimazole applied to the skin. Severe infections, which are rare, require a stronger antifungal drug, such as itraconazole given by mouth. Usually, this disorder is chronic but does not affect lifespan.
Mucocutaneous candidiasis is a superficial fungal infection that may involve almost any cutaneous or mucous surface of the body. It is particularly likely to occur in diabetics, during pregnancy, and in obese persons who perspire freely. Antibiotics and oral contraceptive agents may be contributory. Oral candidiasis may be the first sign of HIV infection. The name Candidi refers to the white color of the infection. It is a heterogeneous disorder of the immune system characterized by persistent yeast infections of the mucous membranes and scalp.
Causes of Mucocutaneous Candidiasis
Common Causes of Mucocutaneous Candidiasis :
Symptoms of Mucocutaneous Candidiasis
Some common Symptoms of Mucocutaneous Candidiasis :
Treatment of Mucocutaneous Candidiasis
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