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Accolate

Brand Names

  • Accolate

General Information

Accolate is a medicine which is used in asthma. Accolate works by directly blocking substances called leukotrienes, which are molecules that contribute to inflammation and narrowing in the airways, a process that leads to symptoms such as difficulty in breathing in patients with asthma. In asthma, Accolate works in the air passages of the lungs to make breathing easier and to help prevent asthma attacks. It is supplied as 10 and 20 mg tablets for oral administration. Accolate should be taken twice every day, whether or not you have had any recent asthma attacks. It works only when used on a regular basis to help reduce inflammation and prevent asthma attacks. It is prescribed for long-term treatment. Zafirlukast, a fine white to pale yellow amorphous powder, is practically insoluble in water. Do not take the medication with food. Accolate should be taken during pregnancy only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately.

Accolate Dosage

  • The dose of this medicine will be different for different patients.
  • Accolate should be taken twice every day, whether or not you have had any recent asthma attacks.
  • The recommended dose of Accolate in adults and children 12 years and older is 20 mg twice daily.
  • The recommended dose of Accolate in children 5through 11 years of age is 10 mg twice daily.

Side Effects of Accolate

The following side effects of Accolate may includes:

  • Generalized pain.
  • Wheezing or continued coughing.
  • Abdominal pain.
  • Yellowing of the eyes or skin.
  • Loss of appetite.
  • Indigestion or mild stomach ache.
  • Weakness.

Warnings and precautions before taking Accolate

  • If you have had an allergic reaction to Accolate or to any of its ingredients, avoid Accolate.
  • While taking Accolate, you should not stop-or even cut down on-any other asthma medication you are using unless your doctor recommends it.
  • This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems.

Overdosage

  • Limited information exists with regard to the effects of overdosage of 'Accolate' in humans.
  • US residents can call the US national poison hotline at 1-800-222-1222.
  • Symptoms of Accolate overdose may include rash and an upset stomach.
  • Canadian residents should call their local poison control center directly.
  • Management should be supportive. Removal of excess medication by gastric lavage may be helpful.

 

 


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