Ibritumomab

Generic Name

• Ibritumomab.

Brand Names

• In-111 Zevalin, Y-90 Zevalin.

General Information

Ibritumomab is a protein that targets white blood cells in the body. Ibritumomab is used in combination with other medicines to treat non-hodgkin's lymphoma. The dose of ibritumomab tiuxetan will be different for different patients. Avoid contact with people who have colds, the flu, or other contagious illnesses. Ibritumomab can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. It is not known whether ibritumomab passes into breast milk or if it could harm a nursing baby. Do not receive ibritumomab without telling your doctor if you are breast-feeding a baby. Ibritumomab is made from human plasma (part of the blood) and may contain infectious agents that can cause disease. Although ibritumomab is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease.

Ibritumomab Dosage

• The dose of ibritumomab will be different for different patients.
• The dose that is used may depend on a number of things, including your size.

Side Effects of Ibritumomab

Some common side effects reported with this medicine include:

• Difficulty breathing.
• Headache.
• Shortness of breath.
• Joint pain.
• Nausea, vomiting.
• Dizziness.
• Unusual weakness.
• Loss of appetite.

Warnings and precautions before taking Ibritumomab

• Do not receive this medication if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
• Avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.
• Avoid sports or other situations where bruising or injury could occur.
• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.
• If you have liver disease, talk with healthcare provider.

Overdosage

• If overdose is suspected, contact your local poison control center or emergency room immediately.
• Symptoms of a ibritumomab overdose tend to be similar to side effects caused by the medication, although possibly more severe.
• US residents can call the US national poison hotline at 1-800-222-1222.

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