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Generic Name

  • Acetaminophen and oxycodone.

Brand Names

  • Endocet, Roxicet, Roxilox, Tylox.

General Information

Endocet is in a class of drugs called narcotic analgesics. This medication is a combination of a narcotic (oxycodone) and a non-narcotic (acetaminophen) used to relieve moderate to severe pain. Acetaminophen comes as a tablet, chewable tablet, capsule, suspension or solution, drops, extended-release tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth), to take by mouth, with or without food. Oxycodone works by binding to opioid receptors in the brain and spinal cord, and acetaminophen decreases the formation of prostaglandins, therefore relieving pain. Acetaminophen also comes as a suppository to use rectally. Acetaminophen is available without a prescription, but your doctor may prescribe acetaminophen to treat certain conditions. Acetaminophen may also be used in combination with aspirin and caffeine to relieve the pain associated with migraine headache.

Endocet Dosage

  • The dose of endocet is variable and depends on the needs of the patient and specific circumstances.

Side Effects of Endocet

Some common side effects reported with this medicine include:

  • Weakness and unconsciousness.
  • Skin rashes.
  • Nausea and vomiting.
  • Headache.
  • Sweating and itching.
  • Dry mouth.
  • Constipation and decreased urination.

Warnings and precautions before taking Endocet

  • Endocet when taken with certain other drugs may change the effect of the medicine. If you are taking any other such as tranquilizers, sedative drugs and antispasmodic drugs, you should consult your doctor before taking endocet.
  • If are addicted to alcohol. Inform your doctor before taking endocet.
  • Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
  • If you are pregnant or plan to pregnant, you should consult your doctor.
  • Do not stop taking the drug without consulting your doctor.
  • You should not take alcohol, while you are on endocet. Alcohol may increase dizziness caused by endocet. Alcohol in combination with acetaminophin can damage liver.
  • If you are allergic to endocet, you should not take the medicine.


  • After taking Endocet, If you feel that overdose is suspected, then contact with your doctor immediately.
  • An overdose of endocet may cause the symptoms like lowr blood pressure, nausea, weakness, sleepiness, slow heartbeat, vomiting, decreased or irregular breathing, color of skin changes to bluish or yellowish.
  • US residents can call the US national poison hotline at 1-800-222-1222.



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